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Meso Scale Diagnostics LLC
u-plex biomarker nhp multiplex assay ![]() U Plex Biomarker Nhp Multiplex Assay, supplied by Meso Scale Diagnostics LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/nhp+protein+multiplex+bead+array/nhp+u+plex+biomarker/pmc08914048-220-18-23 Average 90 stars, based on 1 article reviews
u-plex biomarker nhp multiplex assay - by Bioz Stars,
2026-10
90/100 stars
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Journal: Frontiers in Immunology
Article Title: Simian Immunodeficiency Virus Infection Mediated Changes in Jejunum and Peripheral SARS-CoV-2 Receptor ACE2 and Associated Proteins or Genes in Rhesus Macaques
doi: 10.3389/fimmu.2022.835686
Figure Lengend Snippet: Dynamics of different renin angiotensin system proteins, lactate dehydrogenase, and cytokine production in plasma/serum. (A) Plasma concentration of ACE2 (ng/mL) at different time points of infection. The plasma ACE2 gradually decreased from acute to chronic infection with the lowest concentration at 90 dpi, then recovered during the late chronic stage of infection. (B) Plasma concentration of Angiotensin II (Ang II, pg/mL) at different time points. Though not significant, post infection showed a slight increase of Ang II compared to the pre infection time point, except at 112 and 145 dpi. (C) Plasma concentration of angiotensin II receptor 1 (AGTR1) (ng/mL) during infection. A gradual decrease of plasma AGTR1 was detected from 14 dpi onward. (D) Serum LDH activity (U/L) in infected RMs and uninfected controls were evaluated using a Beckman Coulter AU 480 analyzer. No significant changes in serum LDH activity were detected across the different time points. Plasma IL-6 (E) , IL-1β (F) , and TNF-α (G) concentrations (pg/mL) at pre and post infection time points were evaluated by U-plex biomarker NHP multiplex assay. No significant changes were detected at any time points for any of the proinflammatory cytokines tested. The error bars represent the mean ± SE for each time point (n=10). Each symbol represents individual macaque in each plot. Asterisks indicate statistical differences between time points, as calculated by Bonferroni for ACE2 and Ang II and Tukey-Kramer for AGTR1 (* p < 0.05; ** p < 0.01; *** p < 0.001 and **** p < 0.0001).
Article Snippet: Inflammatory cytokines (IL-1β, IL-6, and TNF-α) and MCP-1 chemokine (monocyte chemoattractant protein-1) in plasma were quantified using a
Techniques: Clinical Proteomics, Concentration Assay, Infection, Activity Assay, Biomarker Discovery, Multiplex Assay